ABSTRACT
Objectives: to find out the frequency of right ventricular infarction [RVI] in patients with acute inferior wall myocardial infarction and also to see its clinical correlation and prognostic value
Methods: 198 consecutive patients with acute inferior wall myocardial infarction [MI] were enrolled. Elevated ST segments in V4R or V3R to V6R were used to diagnose RVI. We assessed the incidence of ST-segment elevation in these leads and their correlation on clinical ground
Result: in 96 patients [48.5%], RVI was present. Clinical correlation showed that raised JVP was present in 58.5% and raised JVP with hypotension in 34.5% of patients. Normal JVP was present in 41.5% of patients in which 22% of patients were with hypotension and 20% of patients were without clinical findings. Hypotension observed in 53% of patients. Complications were higher in patients with elevated ST segments in V4R [51%] in contrast to those without RVI [21%]. In-hospital mortality was more than double in RVI Group
Conclusion: RVI in acute inferior MI is common. Elevated ST segments in V4R or V3R to V6R can be used to diagnose RVI. Clinical correlation can help but may not be diagnostic and it has higher mortality compared to inferior MI alone
ABSTRACT
To determine frequency of Hepatitis E among patients visiting rural health centre Ranipur Sindh. Retrospective study .The study was conducted in patients visiting OPD at rural Health Centre Ranipur from June 2011 To February 2012. The study was conducted in patients visiting OPD with the complaints of gastrointestinal symptoms and jaundice. A designed, structural Performa was filled with the consent of the patients after taking permission from hospital administration. A sample random technique was used to get blood sample and sent to the local laboratory for screening Hepatitis E through Immunochromatography method. 10 to 50 years aged male and female patients were included in the study. The data was analyzed using SPSS 16. Total 2118 patients were screened. 98 [4.27%] cases were positive for Hepatitis E. Among them, the frequency of HEV was highest in children [10-15 years], followed by young adults [16-30] and older adults [31-50]. In all patients, females were 58% and males were 42%. In this study we found significant number of HEV cases, among whom the larger number was from children. In all age groups, females were more affected. Further research should be done for making plans and designed strategies to prevent the epidemic of HEV
ABSTRACT
Objective: To evaluate the efficacy of combined therapy of meglumine antimoniate and co-trimoxazole in cutaneous leishmaniasis [CL]
Methods: 180 patients with active lesions of CL, confirmed by fine needle aspiration cytology [FNAC] were treated with combined therapy of meglumine antimoniate [Glucantime] and co-trimoxazole [Septran] for 20 days
Results: Out of 180 patients, 160 [88.9%] were cured. A few patients reported nausea, vomiting, glossitis, skin rashes and folate deficiency
Conclusion: The combined therapy of meglumine antimoniate [Glucantime] and co-trimoxazole [Septran] is more effective than the previously reported combined therapies
ABSTRACT
During pregnancy, lipid metabolism is remarkably increased due to hormonal changes, which lead to various changes in serum lipid levels. Very high levels of lipids can have adverse effects on the maternal and foetal health. To analyze serum total cholesterol [TC], triglycerides [TGs], low density lipoprotein [LDL] and high density lipoprotein [HDL] in pregnant women during all trimesters. Retrospective [hospital record based] study Place and Duration of Study: This study was carried out in Gynaecology and Obstetrics ward at Liaquat University Hospital, Jamshoro and Hyderabad from March 2011 to February 2012. 5ml blood sample was taken and analyzed for lipid profile using Hitachi 902 chemistry autoanalyzer. The data was analyzed by using SPSS 16. The results showed that all these lipid parameters were raised during the all trimesters of pregnancy in comparison to the control subjects, except that the LDL level was almost equal to the control subjects during the 1[st] trimester. Additionally, comparison showed that Total Cholesterol, Triglycerides and LDL in the 2[nd] and 3[rd] trimesters were significantly higher than in the 1[st] trimester. Serum lipids are significantly increased during the all trimesters of pregnancy. As very high levels of lipids may increase the risk of development of various pregnancy complications for the mother and the developing foetus, lipid profile should be part of routine investigation during pregnancy